Back Bol

The Onboard BOL is the receipt given by the carrier when the shipment has been physically loaded onto a container ship (for ocean freight) or airplane (for air freight). If the carrier determines that the goods are not in good condition when they are received, then they will add a clause. Master bill of lading: with attached underlying bills of lading customer order information customer order number # pkgs weight pallet/slip (circle one) additional shipper info yn yn yn yn yn yn yn yn grand total carrier information handling unit package commodity description ltl only qty type qty type weight h.m.

Medically reviewed by Drugs.com. Last updated on Jan 22, 2021.

• Health Guide

What is Back Pain?

Back pain can be a symptom of many different illnesses and conditions. The main cause of the pain can be a problem with the back itself or by a problem in another part of the body. In many cases, doctors can't find a cause for the pain. When a cause is found, common explanations include:

• Stress or injury involving the back muscles, including back sprain or strain; chronic overload of back muscles caused by obesity; and short term overload of back muscles caused by any unusual stress, such as lifting or pregnancy
• Disease or injury involving the back bones (vertebrae), including fracture from an accident or as a result of the bone-thinning disease osteoporosis
• Degenerative arthritis, a 'wear and tear' process that may be related to age, injury and genetic predisposition.
• Disease or injury involving the spinal nerves, including nerve injury caused by a protruding disk (a fibrous cushion between vertebrae) or spinal stenosis (a narrowing of the spinal canal)

• Kidney stones or a kidney infection (pyelonephritis)
• Inflammatory arthritis, including ankylosing spondylitis and related conditions
• A spinal tumor or a cancer that has spread (metastasized) to the spine from elsewhere in the body
• Infection, which may be in the disk space, bone (osteomyelitis), abdomen, pelvis or bloodstream

• Rarer causes include:

Symptoms

Back pain varies widely. Some symptoms (often called 'red flag' symptoms) may suggest that the back pain has a more serious cause. These include fever, recent trauma, weight loss, a history of cancer and neurological symptoms, such as numbness, weakness or incontinence (involuntary loss of urine or stool).

Back pain is often accompanied by other symptoms that may help point to its cause. For example:

• Back sprain or strain – Back pain typically begins on the day after heavy exertion or an activity that requires twisting. Muscles in the back, buttocks and thighs are often sore and stiff. The back may have areas that are sore when touched or pressed.
• Fibromyalgia – In addition to back pain, there are usually other areas of pain and stiffness in the trunk, neck, shoulders, knees and elbows. Pain may be either a general soreness or a gnawing ache, and stiffness is often worst in the morning. People usually complain of feeling abnormally tired, especially of waking up tired, and they have specific areas that are painful to touch, called tender points.
• Degenerative arthritis of the spine – Together with back pain, there is stiffness and trouble bending over, which usually develops over many years.
• Inflammatory arthritis, including ankylosing spondylitis and related conditions – In these disorders, there is pain in the lower back, together with morning stiffness in the back, hips or both. Back pain in these condition tends to improve with exercise. Other features may include psoriasis, eye pain and redness, or diarrhea, depending on the specific disorder causing back pain. This group of diseases is a relatively rare cause of back pain.
• Osteoporosis – This common condition is characterized by thinned, weakened bones that fracture easily. It is most common in postmenopausal women. When vertebrae become compressed because of fracture, posture may become stooped over or hunched along with back pain. Osteoporosis is not painful unless a bone fractures.
• Cancer in the spinal bones or nearby structures – Back pain is consistent and may become worse when you are lying down. Numbness, weakness or tingling of the legs that continues to get worse. If cancer spreads to spinal nerves that control the bladder and bowel, there may be bowel or bladder incontinence (loss of control).
• Protruding disk – People with significant disk disease sometimes have severe pain in the lower back. If a disk compresses a nerve, the pain may spread down one leg. The pain gets worse during bending or twisting.

• Spinal stenosis – Pain, numbness and weakness affect the back and legs. Symptoms get worse when you are standing or walking, but are relieved by sitting or leaning forward.
• Pyelonephritis – People with a kidney infection typically develop sudden, intense pain just beneath the ribs in the back that may travel around the side toward the lower abdomen or sometimes down to the groin. There also can be a high fever, shaking chills and nausea and vomiting. The urine may be cloudy, tinged with blood or unusually strong or foul-smelling. There may be additional bladder related symptoms, such as the need to urinate more often than normal or pain or discomfort during urination.

Diagnosis

Your doctor will ask about your symptoms and your medical history. He or she will examine your back muscles and spine and will move you certain ways to check for pain, muscle tenderness or weakness, stiffness, numbness or abnormal reflexes. For example, if you have a disk problem, you may have pain in your lower back when the doctor raises your straightened leg.

Your symptoms and the physical examination may give your doctor enough information to diagnose the problem. However, with back pain, your doctor may only be able to tell you that the problem is not serious. If your doctor determines that your back pain is caused by muscle strain, obesity, pregnancy or another cause that is not urgent, you may not need any additional tests. However, if he or she suspects a more serious problem involving your vertebrae or spinal nerves, especially if your back pain has lasted longer than 12 weeks, you may need one or more of the following tests:

• X-rays of your back
• Blood test
• Urine tests
• Spinal magnetic resonance imaging (MRI)
• Computed tomography (CT) scan
• Nerve conduction studies and electromyography to determine whether nerves, muscles or both may be injured
• Bone scan, especially if you have a previous history of cancer

Expected Duration

How long back pain lasts depends on its cause. For example, if your pain is caused by strain from overexertion, symptoms usually subside over days or weeks and you may be able to return gradually to your normal activities. However, you should avoid heavy lifting, prolonged sitting or sudden bending or twisting until your back gets better.

Women who have back pain caused by the added weight of pregnancy almost always will get better after delivery. People who are obese may need to lose weight before back pain eases.

People with back pain caused by pyelonephritis often begin to feel better within days after they start taking antibiotics, although they usually need to continue taking antibiotics for up to two weeks.

People with more serious forms of back pain caused by problems with the vertebrae or spinal nerves may have more persistent back pain that lasts for months and may last for years.

Prevention

You can help prevent some forms of back pain by strengthening your back with exercises and by avoiding activities that lead to back injury. Measures that may help prevent back pain include:

• Maintaining good posture.
• Sleeping on your side or on your back with a pillow under your knees if you can.
• Exercising regularly, but stretch before and after.
• Practicing abdominal crunches to strengthen abdominal muscles, which support your lower back. Also, walk or swim regularly to strengthen your lower back.
• Always lifting objects from a squatting position, using your hips and your legs to do the heavy work. Avoid lifting, twisting and bending at the same time.

• Avoiding sitting or standing for extended periods of time.
• Wearing soft soled shoes with heels that are less than 1 and one-half inches high.

To help prevent osteoporosis, make sure you get enough calcium and vitamin D daily to meet the dietary requirements for your age group. Follow a routine program of weight-bearing exercise. Avoid smoking and limit the amount of alcohol you drink. If you are a woman who has entered menopause, speak with your doctor about testing for osteoporosis and medications that can help to prevent or reverse it.

Treatment

Most episodes of back pain are not serious and may be treated with:

• Limited bed rest (no more than two days)
• Acetaminophen (Tylenol and others) for pain or oral anti-inflammatory drugs, such as aspirin, ibuprofen (Advil, Motrin and others) or naproxen (Aleve, Naprosyn), for pain and inflammation
• Muscle relaxants or prescription pain relievers, if necessary, for a short period
• Hot or cold compresses

People with back pain are encouraged to return to their normal activities gradually, and to temporarily avoid heavy lifting, prolonged sitting, or sudden bending or twisting.

If you are recovering from back pain, your doctor may ask you to call or return to his or her office for a follow-up visit in about two weeks to confirm that your symptoms are gone and that you can safely resume all of your normal activities.

If your back pain is related to more serious disorders of the vertebrae or spinal nerves or if it hasn't improved over a few weeks, you may be referred to a specialist, such as a pain specialist, an orthopedic surgeon (a doctor who specializes in diseases of the bones), a neurologist (a doctor who specializes in diseases of the nerves and brain) or a rheumatologist (an arthritis specialist).

When To Call a Professional

Contact your doctor if:

• Severe back pain makes it impossible for you to do your normal daily activities.
• Your back pain follows significant trauma.
• Mild back pain gets worse after a few days or persists more than a week or two.
• Back pain is accompanied by weight loss, fever, chills or urinary symptoms.
• You develop sudden weakness, numbness or tingling in a leg.
• You develop numbness in the groin or rectum or difficulty controlling bladder or bowel function.
• You have had cancer previously and you develop persistent back pain.

Prognosis

Back Bolster

More than 90% of people with back pain get better after conservative treatment. Only 5% of people with back pain will have symptoms for more than 12 weeks and even among these people, the cause is usually not serious.

Learn more about Back Pain

Associated drugs

IBM Watson Micromedex

Mayo Clinic Reference

External resources

American Academy of Orthopaedic Surgeons (AAOS)
http://orthoinfo.aaos.org/

Back Bolsters

American College of Rheumatology
http://www.rheumatology.org/

Arthritis Foundation
http://www.arthritis.org/

National Institute of Arthritis and Musculoskeletal and Skin Diseases
http://www.niams.nih.gov/

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Is Dianabol a Banned Steroid or a Legal Supplement

Dianabol once contained the now-banned ingredients metandienone and methandrostenolone. Dianabol, sold under the brand name of CiBa Labs. The ingredient methandrostenolone, no longer used in medicine in the United States. The extensive side effects forced the FDA to discontinue all Dianabol products containing methandrostenolone. Even though effective Dianabol alternatives, uninformed bodybuilders still use the old D-Bol and choose to accept the possible risks. Taken orally by mouth in capsule form.

Side Effects of Methenandrostenolone

Side effects 0f methandrostenolone may include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire, estrogenic effects like fluid retention and breast enlargement, and liver damage. The drug is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT), and has strong anabolic effects and moderate androgenic effects. It also has moderate estrogenic effects.

Dianabol e.g, D-BOL, originally developed in 1955 by CIBA and marketed in Germany and the United States. As the CIBA product Dianabol, Dianabol e.g, D-BOL quickly became the first widely used AAS among professional and amateur athletes, and remains the most common orally active AAS for non-medical use. It is currently a controlled substance in the United States and United Kingdom and remains popular among bodybuilders. Dianabol e.g, D-BOL (absent of the ingredient Methandrostenolone) is now established as a dietary supplement, and is readily available without a prescription in certain countries.

Previous Medical Uses

Dianabol e.g, D-BOL was formerly approved and marketed for the treatment of hypogonadism, but has since been discontinued and withdrawn in most countries. As of the removal of the ingredient methandrostenolone, Dianabol is presently available as an over-the-counter dietary supplement in the USA.

Use For Muscle Building

Dianabol, or D-BOL, is used as a bodybuilding supplement for it’s performance-enhancing purposes. Competitive athletes, bodybuilders, and powerlifters use it for muscle growth, recovery, and strength promotion. It is said to be the most widely used legal-steroid for such purposes both today.

Side Effects and Safer Alternatives

Androgenic side effects such as oily skin, acne, seborrhea, increased facial/body hair growth, scalp hair loss, and virilization may occur. Estrogenic side effects such as gynecomastia and fluid retention can also occur, but is not typical with the legal dianabol supplements. As with other 17α-alkylated steroids, methandrostenolone poses a risk of hepatotoxicity and use over extended periods of time can result in liver damage without appropriate precautions. Diandrobol by Muscle Labs USA is non-methylated and poses little to no risk when taken at recomended doses.

Pharmacology

Methandrostenolone binds to and activates the androgen receptor (AR) in order to exert its effects. These include dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time.[medical citation needed] While it can be metabolized by 5α-reductase into methyl-1-testosterone (17α-methyl-δ1-DHT), a more potent AAS, the drug has extremely low affinity for this enzyme and methyl-1-testosterone is thus produced in only trace amounts. As such, 5α-reductase inhibitors like finasteride and dutasteride do not reduce the androgenic effects of Dianabol e.g, D-BOL. Nonetheless, while the ratio of anabolic to androgenic activity of Dianabol e.g, D-BOL improved relative to that of testosterone, the supplement does still possess moderate androgenic activity, capable of producing severe virilization in women and children. As such, only really commonly used in men.

Methandrostenolone, a substrate for aromatase, metabolized into the estrogen methylestradiol (17α-methylestradiol). While the rate of aromatization reduced relative to that for testosterone or methyltestosterone, the estrogen produced is metabolism-resistant. The Dianabol supplement e.g, D-BOL retains little estrogenic activity. As such, side effects such as gynecomastia and fluid retention not expected with the legal Dianabol. The co-administration of an antiestrogen such as an aromatase inhibitor like anastrozole or a selective estrogen receptor modulator like tamoxifen will reduce or prevent estrogenic side effects. D-BOL has no progestogenic activity.

As with other 17α-alkylated AAS, Methandrostenolone is hepatotoxic, however the new Dianabol e.g, D-BOL supplements are NOT.

Pharmacokinetics

Back Bolster For Chair

Dianabol e.g, D-BOL has high oral bioavailability. It has very low affinity for human serum sex hormone-binding globulin (SHBG), about 10% of that of testosterone and 2% of that of DHT. The drug metabolized in the liver by 6β-hydroxylation, 3α- and 3β-oxidation, 5β-reduction, 17-epimerization, and conjugation among other reactions. Unlike methyltestosterone, owing to the presence of its C1(2) double bond, Dianabol e.g, D-BOL does not produce 5α-reduced metabolites. The elimination half-life of Dianabol e.g, D-BOL is about 3 to 6 hours. Eliminated in the urine.

D-Bol Chemistry

Methandrostenolone, also known as 17α-methyl-δ1-testosterone or as 17α-methylandrost-1,4-dien-17β-ol-3-one, is a synthetic androstane steroid and a 17α-alkylated derivative of testosterone. It is a modification of testosterone with a methyl group at the C17α position and an additional double bond between the C1 and C2 positions. The drug is also the 17α-methylated derivative of boldenone (δ1-testosterone) and the δ1 analogue of methyltestosterone (17α-methyltestosterone).

Drug Testing and Detention of Use

Dianabol e.g, D-BOL is subject to hepatic biotransformation by a variety of enzymatic pathways. The primary urinary metabolites detectable for up to 3 days, and a recently discovered hydroxymethyl metabolite found in urine for up to 19 days after a single 5 mg. oral dose. Several of the metabolites are unique to Dianabol e.g, D-BOL. Methods for detection in urine specimens usually involve gas chromatography-mass spectrometry.

History Of D-Bol Use In Sports

Dianabol containing Methandrostenolone was first desgined in 1955. Synthesized by researchers at the CIBA laboratories in Basel, Switzerland. CIBA filed for a U.S. patent in 1957, and began marketing the drug as Dianabol in 1958 in the U.S. Initially prescribed to burn victims and the elderly. Also prescribed off-label as a pharmaceutical performance enhancement to weight lifters and other athletes. Early adopters included players for Oklahoma University and San Diego Chargers head coach Sid Gillman, who administered Dbol to his team starting in 1963. Later it became known as the choice anabolic-supplement of a Professional bodybulder named Arnold Schwarzenegger.

Back Boleo Technique

Legal – FDA Vs. Ciba

After the Kefauver Harris Amendment passed in 1962, the U.S. FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol. In 1965, the FDA pressured CIBA to further document methandrostenolone’s legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism. After CIBA’s patent exclusivity period lapsed, other manufacturers began to market generic “Dianabol” in the U.S.

Following further FDA pressure, CIBA withdrew the methndrostenolone Dianabol from the U.S. market in 1983. Generic production shut down two years later, when the FDA revoked Dianabol e.g, D-BOL’s approval entirely in 1985. Non-medical use of methandrostenolone outlawed in the U.S. under the Anabolic Steroids Control Act of 1990. While methandrostenolone is controlled and no longer medically available in the U.S., products continue to be produced and sold legally in the United States absent of any banned ingredients under such names as DIANDROBOL™, DIANADROL®, DIANABOLIC™, and D-Anobol™.

Back Bolster Cushion

Dianabol with Methandrostenolone confiscated by the Drug Enforcement Administration (DEA) in 2008.

Back Bolster Dog Bed

Brand names

Methandrostenolone was originally introduced and formerly sold under the brand name “Dianabol”. It has also been marketed under a variety of other brand names including Anabol, Averbol, Chinlipan, Danabol, Dronabol, Metanabol, Methandon, Naposim, Reforvit-B, and Vetanabol among others. Dianabol is now a registered dietary supplement, which many refer to as a “legal steroid” supplement.

Legal status

Methandrostenolone, along with other androgenic anabolic steroids, a schedule III controlled substance in the United States under the Controlled Substances Act. The NEW DIANDROBOL supplement does not contain that ingredient and therefore, NOT illegal or dangerous. Marketed as a dietary supplement for bodybuilders that want bulk up. It is worth noting that “Dianabol” currently sold as a legal dietary supplement in the United States. Dianabol is LEGAL, as long as it does not contain methandrostenolone. All old versions of Dianabol containing methandrostenolone are illegal.